Justin Jones Receives ACS Award
Dr. Justin Jones, Postdoc in the Cheng lab, received a 3 year, $150k American Cancer Society grant entitled, "Biochemical and Inhibition Studies of Histone H3 Jumonji Demethylases." Dr. Jones's research will focus on the structure, regulation, and inhibition of jumonji-domain containing histone demethylases. These enzymes are involved in the tumorigenesis of gastric, breast, and prostate cancers. Target based drug design, high-throughput screening techniques, and x-ray crystallography will be performed to identify inhibitors of these enzymes as potential chemotherapeutics.