David C. Pallas, PhD
Emory University School of Medicine
Office: 4125 Rollins Research Center
Emory University Department of Biochemistry
1510 Clifton Rd.
Rollins Research Center
Atlanta, GA 30322
Research FocusThe primary purpose of the research in my laboratory is to understand the molecular basis of the control of cell proliferation and of mechanisms by which this control is circumvented in neoplastic cell growth. Our approach has been to investigate the roles of a set of cellular proteins which associate with polyomavirus small and/or middle tumor (T) antigens. Middle T antigen (MT) is capable of transforming a wide variety of cell types to a state of uncontrolled cell proliferation. In some
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Global loss of leucine carboxyl methyltransferase-1 causes severe defects in fetal liver hematopoiesis.
Lee JA, Wang Z, Sambo D, Bunting KD, Pallas DC.
J Biol Chem. 2018 Jun 22;293(25):9636-9650. doi: 10.1074/jbc.RA118.002012. Epub 2018 May 7.